得益于雷根斯堡在RNA生物学方面的专业知识、其独特的菌株库以及在培养嗜极古菌方面的专门技术，这项新技术被证明特别有效。因此，在本研究中，能够使用到最适生长温度高达113°C的超嗜热古菌世界纪录保持者。

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

本研究针对血吸虫病治疗药物单一、耐药性风险高等问题，系统开展了非寄生虫基因组编码RNA (ngRNA)在日本血吸虫 (S.japonicum)致病性调控中的作用研究。研究人员通过宏转录组学、单细胞RNA测序等技术，首次发现4种ngRNA通过编码RNA依赖性RNA聚合酶 (RdRp)调控血吸虫卵巢发育和产卵过程，并证实靶向rp1 ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

细菌与噬菌体之间的军备竞赛已经持续了数十亿年。这场没有硝烟的战争催生了地球上最复杂、最精巧的防御系统。当我们以为自己已经通过Cas9、Cas12a或Cas13窥探到了CRISPR-Cas系统的全貌时，自然界总能以一种令人惊叹的方式提醒我们：我们所知的 ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

Eight years ago, 10x Genomics launched the first commercially available single-cell RNA sequencing (scRNA-seq) product for the company’s flagship instrument, the 10x Chromium. (This occurred one year ...

Programmable nucleic acid nanoparticles boost vaccine immune responses as effectively as standard adjuvants in mice while ...

Researchers analyzed gene expression and network connectivity across eight human tissues and found shared aging-related ...

Factorial Biotechnologies, a leader in next-generation single-cell sequencing solutions, and Honeycomb Biotechnologies, a pioneer in instrument-free single-cell analysis, today announced a strategic ...